Publications

AI & risk modeling

  • Ashar Ahmad, Holger Fröhlich (2017)
    Towards clinically more relevant dissection of patient heterogeneity via survival-based Bayesian clustering
    Bioinformatics, 33(22), 3558-3566, https://doi.org/10.1093/bioinformatics/btx464
  • Thomas Gerlach, Chao Lu, Holger Fröhlich (2017)
    Predicting comorbidities of epilepsy patients using big data from Electronic Health Records combined with biomedical knowledge
    Proc. of the German Conference on Bioinformatics 2017/, 5:e3228v1, https://doi.org/10.7287/PEERJ.PREPRINTS.3228V1
  • Shashank Khanna, Daniel Domingo-Fernandez, Anandhi Iyappan, Mohammad Asif Emon, Martin Hofmann-Apitius, Holger Fröhlich (2018)
    Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer's Disease and Reconstruction of Relevant Biological Mechanisms
    Nature Scientific Reports, 8, Article number: 11173, https://www.nature.com/articles/s41598-018-29433-3
  • Colin Birkenbihl, Mohammad Asif Emon, Henri Vrooman, Sarah Westwood, Simon Lovestone, On behalf of the AddNeuroMed Consortium, Martin Hofmann-Apitius, Holger Fröhlich (2020)
    Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice
    EPMA Journal, 11(3):367-376, https://doi.org/10.1007/s13167-020-00216-z

COVID-19 Terminology, Ontology & Knowledge Graphs

  • Daniel Domingo-Fernández,  Shounak Baksi,  Bruce Schultz,  Yojana Gadiya, Reagon Karki,  Tamara Raschka,  Christian Ebeling,  Martin Hofmann-Apitius, Alpha Tom Kodamullil (2020)
    COVID-19 Knowledge Graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology
    Bioinformatics, btaa834, https://doi.org/10.1093/bioinformatics/btaa834
  • Bruce Schultz,  Andrea Zaliani,  Christian Ebeling, Jeanette Reinshagen, Denisa Bojkova, Vanessa Lage-Rupprecht, Reagon Karki, Sören Lukassen, Yojana Gadiya, Neal G. Ravindra,  Sayoni Das,  Shounak Baksi, Daniel Domingo-Fernández, Manuel Lentzen, Mark Strivens, Tamara Raschka,  Jindrich Cinatl, Lauren Nicole DeLong, Phil Gribbon,  Gerd Geisslinger, Sandra Ciesek, David van Dijk, Steve Gardner, Alpha Tom Kodamullil, Holger Fröhlich, Manuel Peitsch, Marc Jacobs, Julia Hoeng, Roland Eils, Carsten Claussen, artin Hofmann-Apitius (2020)
    The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization.
    bioRxiv, https://www.biorxiv.org/content/10.1101/2020.09.23.308239v1.abstract