Data

COVID-19 Datasets Viewer#

Clinical Studies

Metadata of the studies included in the viewer.

Publication reference URL of Dataset Clinical Trial ID Country Country code Study design Total number of subjects Ethnicity Existent variables Exclusion criteria Inclusion criteria Demographic Clinical variables Laboratory variables Comorbidities Drugs Imaging Endpoint Type of data
https://doi.org/10.1101/2020.07.07.20148304 NaN NaN USA USA Cross-sectional 3927 NaN Demographic|Clinical|Laboratory|Comorbidities NaN NaN Age|Sex Heart Rate|Oxygen Saturation|Temperature Alanine aminotransferase|Aspartate aminotransferase|Blood glucose|Blood urea nitrogen|C-Reactive protein|Creatinine|Hemoglobin|Corpuscular volume|Platelet count|Potassium|Prothrombin time|Sodium|White blood cell count Cardiac dysrhythmias|Chronic kidney disease|Heart disease|Diabetes NaN NaN NaN Structured
NaN NaN NaN USA USA Cross-sectional 3661 NaN Demographic|Clinical|Laboratory|Imaging NaN Chest X-ray images linked to radiology reports & encounter information|Discharged patients|Chest X-rays collected prior to any adverse events|Non-intubated based on manual annotation Age|BMI Heart Rate|Respiratory rate|Temperature|Systolic blood pressure|Diastolic blood pressure|Oxygen Saturation Albumin|Alanine aminotransferase|Aspartate aminotransferase|Total bilirubin|Blood urea nitrogen|Calcium|Chloride|Creatinine|D-Dimer|Eosinophil count|Eosinophil percentage|Hematocrit|Lactate dehydrogenase|Lymphocyte percentage|Lymphocyte count|Platelet volume|Neutrophil count|Neutrophil percentage|Platelet count|Potassium|Procalcitonin|Total protein|Sodium|Troponin level NaN NaN X ray NaN Mixed
https://doi.org/10.1101/2020.04.26.20073411 NaN NaN USA USA Cross-sectional 3055 Non-Hispanic|Latino|Hispanic|Latino|Unknown Demographic|Clinical|Laboratory|Comorbidities NaN Inpatient|Age greater than 18|Positive result or RT-PCR SARS CoV-2 lab test|COVID 19 lab order less than equal to 48 hr after admit|Incubation time less than equal to 48 hr from admit|Death time after admit time Age|Sex Heart Rate|Pulse|Respiration Rate|Temperature|Systolic blood pressure|Diastolic blood pressure Sodium|Potassium|Creatinine|Lactate|White blood cell count|Lymphocyte percentage|Hemoglobin|Red blood cell distribution width|Platelet count|Alanine aminotransferase|Aspartate aminotransferase|Albumin|Total bilirubin|Prothrombin time|Partial Prothrombin time|PCO2|pH|C-Reactive protein|Ferritin|D-Dimer|Creatinine phosphokinase|Lactate dehydrogenase|Troponin level Hypertension|Atrial fibrillation|Coronary artery disease|Heart failure|Stroke|Chronic kidney disease|Diabetes|Asthma|Chronic obstructive pulmonary disease|Cancer NaN NaN NaN Structured
https://doi.org/10.1101/2020.04.23.20076737 NaN NCT04280705 USA USA Observational 217 White|Black|Asian|Other|Unknown Demographic|Laboratory|Drugs|Comorbidities NaN NaN Age|Sex|BMI ICU days|Hospital days|Ventilator days|Vassopressor days D-Dimer|C-Reactive protein|PaO2/FiO2 Hypertension|Congestive heart failure|Coronary artery disease|Diabetes|Asthma|Chronic obstructive pulmonary disease|Chronic kidney disease/ end stage renal disease| Hydroxychloroquine|Remdesivir NaN NaN NaN
https://doi.org/10.1016/S0140-6736(20)31189-2 NaN NaN USA USA Longitudinal 257 Black or African American|Hispanic or Latino|White|Asian|Other Demographic|Clinical|Laboratory|Comorbidities|Drugs NaN NaN Age|Sex|BMI Temperature|Heart Rate|Respiratory rate|Systolic blood pressure|Oxygen Saturation|Altered mental status Lactate|Creatinine|Proteinuria|Urine protein concentration|White blood cell count|Lymphocyte count|Platelet count|Bilirubin|Aspartate aminotransferase|Alanine aminotransferase|Creatine kinase|Prothrombin time|Interleukin-6|High-sensitivity C-Reactive protein|Ferritin|D-Dimer|High-sensitivity Troponin|Procalcitonin Hypertension|Diabetes|Chronic Cardiac arrest (excluding hypertension)|Chronic kidney disease|Current or former smoker|Chronic obstructive pulmonary disease or interstitial Lung disease|Chronic neurological disease or dementia|Asthma|Active solid or haematological malignancy or dysplasia|Solid organ Transplantion recipient|HIV|Liver cirrhosis Hydroxychloroquine|Remdesivir NaN NaN Structured
https://doi.org/10.1136/bmj.m1996 NaN NaN USA USA Observational 1000 Asian|Black or African American|Hispanic or Latino|Not specified|Other|White Demographic|Comorbidities|Drugs NaN NaN Age|Sex|BMI NaN NaN Hypertension|Diabetes|Coronary artery disease|Congestive heart failure|Pulmonary disease|Asthma|Chronic obstructive pulmonary disease|Obstructive sleep apnea|Interstitial Lung disease|Renal disease|History of stroke|Active cancer|Transplantion history|Rheumatalogic disease|HIV|Viral hepatitis|Cirrhosis|Obesity ACEi|NSAIDs|Statinss|Diuretics|Inotropes|Vasopressors|Intravenous immunoglobulin|Steroidss|Hydroxychloroquine|Tocilizumab|Remdesivir|Lopinavir/Ritonavir|Azithromycin|Ceftriaxone|Doxycycline|Levofloxacin|Meropenem|Piperacillin/tazobactum|Vancomycin|Other antibiotics NaN NaN Unstructured
https://doi.org/10.1002/ejhf.1924 NaN NaN UK GBR Interventional 12000 Caucasian|Black|Asian|Unknown|Mixed|Other Demographic|Laboratory|Comorbidities|Drugs NaN Admission of symptomatic patients Age|Sex|BMI NaN Systolic blood pressure|Diastolic blood pressure Hypertension|Diabetes|Heart failure|Ischaemic Heart Disease|Chronic obstructive pulmonary disease|Asthma|Chronic kidney disease|Previous stroke/TIA ACEi|ARB|Statins|Beta-blocker NaN Death|Critical Care|Alive NaN
https://doi.org/10.1101/2020.03.21.20040691 NaN NCT04275245 China CHN Interventional 39 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.04.06.20054890 NaN NaN China CHN Observational 97 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Structured
https://doi.org/10.1016/j.jinf.2020.03.002 NaN NaN China CHN Interventional 33 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Structured
https://doi.org/10.1101/2020.04.08.20057539 NaN NaN China CHN Observational 564 NaN Demographic|Laboratory|Comorbidities|Drugs|Imaging Without available clinical or imaging data|Age less than 18 years NaN Age|Sex NaN Hemoglobin|Platelet count|Neutrophil count|Leukocyte count|Alanine aminotransferase|Aspartate aminotransferase|Total bilirubin|Albumin|Blood urea nitrogen|Creatinine|Sodium|Potassium|Creatine kinase|Lactose dehydrogenase|D-Dimer|Procalcitonin|C-Reactive protein|Abnormal CT findings|Lung CT score Hypertension|Diabetes|Cardiovascular disease|Chronic obstructive pulmonary disease|Cerebrovascular disease|Chronic renal disease|Hepatitis B/C|Malignancy|Immunodeficiency Arbidol|Lopinavir/Ritonavir|Interferon-α CT scan Severe pneumonia NaN
https://doi.org/10.1056/NEJMoa2007016 NaN NaN USA|Europe|Japan USA|JPN Interventional 61 NaN Demographic|Laboratory|Comorbidities|Drugs| NaN NaN Age|Sex NaN Alanine aminotransferase|Aspartate aminotransferase|Creatinine Any condition|Hypertension|Diabetes|Hyperlipidemia|Asthma Remdesivir NaN Death|Critical Care|Alive Structured
https://doi.org/10.1101/2020.04.01.20048561 NaN NCT04322188 Italy ITA Interventional 30 NaN Demographic|Laboratory|Comorbidities|Drugs| NaN NaN Age|Sex|Height|Weight NaN White blood cell count|Hemoglobin|Platelet count|Lymphocyte count|Monocyte count|Neutrophil count|Alanine aminotransferase|Aspartate aminotransferase|Creatinine|Procalcitonin|Lactate dehydrogenase|Interleukin-6|C-Reactive protein Hypertension|Diabetes|Cardiovascular disease|Malignancy|Cerebrovascular disease|Chronic kidney disease Siltuximab NaN Reduces morality associated with COVID 19 and respiratory failure Structured
https://doi.org/10.1101/2020.03.25.20037721 NaN NaN China CHN Interventional 323 NaN Demographic|Laboratory|Comorbidities|Drugs|Imaging NaN NaN Age|BMI|Sex|Temperature|Hypnotics|Smoking history|Drinking NaN White blood cell count|Neutrophil count|Lymphocyte count|Platelet count|C-Reactive protein|Serum Amyloid A|Hypersensitive troponin|Prothrombin time|Creatine kinase|Lactate dehydrogenase|Alanine aminotransferase|Aspartate aminotransferase|Blood urea nitrogen|Creatinine|Glucose|RT-PCR Cirrhosis|Hypertension|Diabetes|Malignancy|Cerebrovascular disease|Chronic obstructive pulmonary disease|Chronic kidney disease|Chronic liver disease|Cardiovascular and cerebrovascular diseases|Digestive system disease|Endocrine system disease|Nervous system disease|Respiratory disease Oseltamivir|Ganciclovir|Arbidol|Kaletra|Interferon-α|Antibiotics|CorticoSteroids/glucocorticoid CT scan NaN Structured
https://doi.org/10.1101/2020.04.11.20061473 NaN NCT04320238 China CHN Interventional 2944 NaN Dermographic|Drugs NaN Official members of Taihe Hospital Medical staff Age|Sex NaN NaN NaN Interferon-α|Thymosin-α1 NaN NaN Structured
https://doi.org/10.1101/2020.04.15.20067017 NaN NaN Brazil BRA Interventional 27 NaN Demographic|Laboratory|Comorbidities|Drugs NaN NaN Age|Sex NaN D-Dimer|Lactate dehydrogenase|Platelet count|PaO2/FiO2 Breast cancer|Atrial fibrillation|Obesity|Hypertension|Chronic obstructive pulmonary disease|Parkinson disease|Diabetes|Coronary heart disease|Hyperthyrodisim|Asthma|Cerebrovascular disease|Treated lymphoma|Tobacco dependence Heparin NaN Discharged NaN
https://doi.org/10.1101/2020.04.22.20075671 NaN NaN USA USA|JPN Interventional 490 Hispanic|Non Hispanic|Unknown Demographic|Comorbidities|Drugs|Imaging NaN Inpatients with COVID 19|Inpatients with COVID 19 administered with AZ and/or HCQ|Patients with greater than 2 ECGs Age|Sex|BMI NaN NaN Heart failure|Hypertension|Diabetes|Chronic kidney disease|Chronic obstructive pulmonary disease Azithromycin|Hydroxychloroquine ECG NaN Structured
https://doi.org/10.1002/jmv.25893 NaN NaN China CHN Interventional 184 NaN Demographic|Laboratory|Drugs|Imaging NaN NaN Age|Sex NaN Alanine aminotransferase|Aspartate aminotransferase|Leukocyte count|Neutrophil count|Lymphocyte count|Erythrocyte sedimentation rate NaN Arbidol|Lopinavir/Ritonavir|Interferon-α|Darunavir CT scan NaN Structured
https://doi.org/10.1101/2020.03.28.20046144 NaN chiCTR2000030700 China CHN Observational 42 NaN Demographic|Laboratory|Comorbidities|Drugs Patients received glucocorticoids|Patients received immunepreparations|Patients with chronic infectious diseases|Patients had no cytokine test|Patients with liver and kidney insufficiency|Patients received Low Molecular Weight Heparin (LMWH) in the previous three months NaN Age|Sex NaN Respiratory rate|Pulse|Systolic blood pressure Hypertension|Diabetes|Cardiovascular disease|Chronic obstructive Lung disease|Carcinoma|Chronic kidney disease Arbidol|Recombinant human Interferon-α2B (aeresol inhalation)|Ribavirin|Lopinavir/Ritonavir|Traditional medicine|Heparin NaN NaN Structured
https://doi.org/10.1101/2020.04.21.20066258 NaN NaN China CHN Interventional 115 NaN Demographic|Laboratory|Comorbidities|Drugs NaN Patients diagnosed with COVID 19|Corticosteriod therapy Age|Sex NaN White blood cell count|Lymphocyte count|Serum potassium|Creatinine|Lactate dehydrogenase|Serum Amyloid A|C-Reactive protein|Erythrocyte sedimentation rate|Creatine kinase|Albumin|D-Dimer| Hypertension|Cardiovascular disease|Diabetes Corticosteriod NaN NaN Structured
https://doi.org/10.1101/2020.03.06.20032342 NaN NaN China CHN Interventional 46 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs|Imaging NaN NaN Age|Sex Temperature|Heart Rate|Systolic pressure|Diastolic blood pressure|Respiratory rate|SpO2 at rest White blood cell count|Lymphocyte count|Neutrophil count|C-Reactive protein|Procalcitonin|Interleukin-2|Interleukin-4|Interleukin-6|Interleukin-10|Ferroprotein Chronic Cardiac arrest|Chronic obstructive pulmonary disease|Cerebrovascular disease|Malignancy|Diabetes|Hypertension Methylprednisolone CT scan NaN Structured
https://doi.org/10.1089/scd.2020.0080 NaN NaN USA USA Observational 24 NaN Demographic|Laboratory|Comorbidities|Drugs NaN Age between 18 and 85 years|Positive result on SARS-CoV-2 polymerase chain reaction (PCR)|Presentation of fever and/or dyspnea for greater than 72 h|Overall clinicaldeterioration as evidenced by downtrending PaO2/FiO2 Age|Sex|BMI|Weight|Height NaN PaO2/FiO2 Hypertension|Hyperlipidemia ExoFlo NaN Recovered|Crticical Care Structured
https://doi.org/10.1016/j.eng.2020.03.007 NaN ChiCTR2000029600 China NaN Observational 91 NaN Demographic|Laboratory|Comorbidities|Drugs|Imaging NaN Age between 16 and 75 years old|Nasopharyngeal swabs samples tested positive for the novel coronavirus|Duration from disease onset to enrolment less than 7 days|Willing to take contraception during the study and within 7days after treatment|No difficulty in swalloing the pills. Age|Sex|BMI NaN White blood cell count|Neutrophil count|Lymphocyte count|Alanine aminotransferase|Aspartate aminotransferase|Gamma glutamyl transpeptidase|C-Reactive protein|Interleukin-6|T lymphocyte count|CD4+ lymphocyte count|CD8+ lymphocyte count Myalgia|Diarrhoea Favipiravir|Lopinavir/Ritonavir CT scan Adverse reactions like Diarrhoea|Vomiting|Nausea|Rash|Liver and Kidney injury|Others Structured
NaN NaN NaN Italy ITA Interventional 63 NaN Demographic|Laboratory|Comorbidities|Drugs NaN Polymerase chain reaction confirmed|Pulmonary involvment, assessed either by oxygen saturation (SaO2) of less than 93% if they were breathing ambient air, or a ratio of partial pressure of oxygen (PaO2) to the fraction of inspired oxygen ( FiO2) of less than 300 mmHg|Markedly deranged proinflammatory and prothrombotic profile (at least 3 of the following): CRP greater than x 10 normal values, D-Dimer x 10 normal values, Lactate dehydrogenase x 2 the upper limits Age NaN D-Dimer|C-Reactive protein|Ferritin|Lymphocyte count|Interleukin-6 Hypertension|Diabetes|Heart disease|Chronic obstructive pulmonary disease Tocilizumab NaN NA NaN
https://doi.org/10.1001/jamacardio.2020.1834 NaN NaN USA USA Interventional 90 NaN Demographic|Laboratory|Comorbidities|Drugs NaN NaN Age|Sex|BMI NaN Serum creatinine|White blood cell count|Absolute lymphocyte count|Maximum temperature on day of treatment initiation|C-Reactive protein|Creatine phosphokinase|D-Dimer|Lactate dehydrogenase|Ferritin Hypertension|Congestive heart failure|Diabetes|Coronary artery disease|Atrial fibrillation|Chronic obstructive pulmonary disease|Asthma Hydroxychloroquine|Azithromycin NaN NaN Structured
https://doi.org/10.1016/j.autrev.2020.102568 NaN NaN Italy ITA Interventional 100 NaN Demographic|Laboratory|Comorbidities|Drugs NaN NaN Age|Gender NaN White blood cell count|Neutrophil count|Lymphocyte count|Platelet count|Hemoglobin|C-Reactive protein|Interleukin-6|Ferritin|D-Dimer|Fibrinogen|Aspartate aminotransferase|Alanine aminotransferase|Lactate dehydrogenase|Triglycerides|Cholesterol|Creatine kinase|Troponin level Arterial hypertension|Diabetes|Cardiovascular disease|Chronic kidney disease|Chronic obstructive pulmonary disease|Malignancy|Obesity Lopinavir/Ritonavir|Remdesivir|Azithromycin|Ceftriaxone|Piperacillin/tazobactum|Hydroxychloroquine|Dexamethasone NaN NaN Structured
https://doi.org/10.1016/j.medmal.2020.05.001 NaN NaN France FRA Interventional 20 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs|Imaging NaN NaN Age|Sex|BMI quick-Sequential Organ Failure Assessment|Blood Pressure|Confusion or Glasglow scale|Respiratory rate|Oxygen Saturation Lymphocyte count|C-Reactive protein Hypertension|Diabetes|Chronic obstructive pulmonary disease|Immunosuppression|Malignancy Tocilizumab CT scan Death|ICU admission|Discharge Structured
https://doi.org/10.3390/microorganisms8050695 NaN NaN Italy ITA Interventional 112 NaN Demographic|Laboratory|Comorbidities|Drugs NaN NaN Sex|Age NaN Lactate dehydrogenase|Lymphocyte count|Neutrophil count|Alanine aminotransferase|C-Reactive protein|Procalcitonin|Prolactonin|PaO2/FiO2 Past tumor|Hypertension|Heart disease|Diabetes|Obesity|Lung disease|Other comorbidities Tocilizumab NaN NaN Structured
https://doi.org/10.1016/j.phrs.2020.104899 NaN NaN Italy ITA Interventional 50 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs NaN Male or non pregnant fenale aged greater than 18|SARS CoV-2 infection confirmed by postive RT PCR test|Had mechanical ventilation or oxygen saturation (SaO2)level of less than 94% in room air|National Early Warning Score (NEWS)2 greater than equal to 4 Age|Sex Temperature FiO2|PaO2/FiO2|National Early Warning Score 2 (NEWS2)|White blood cell count|Lymphocyte count|Platelet count|Prothrombin time|D-Dimer|Alanine aminotransferase|Lactate dehydrogenase|C-Reactive protein|Serum creatinine Diabetes|Hypertension|Cancer|Obesity Remdesivir NaN Hospitalization|Death|Disharge Structured
https://doi.org/10.1101/2020.05.02.20080036 NaN NaN USA USA Interventional 900 African American|White|Asian|Other|Multiracial|Unknown Demographic|Clinical|Laboratory|Comorbidities NaN NaN Age|Sex|BMI Respiratory rate|Oxygen Saturation|Pulse|Systolic blood pressure|Diastolic blood pressure|Temperature White blood cell count|Absolute neutrophil count|Absolute lymphocyte count|Ferritin|D-Dimer|Troponin level|Creatine Phosphokinase|Procalcitonin|Creatinine|C-Reactive protein| Hypertension|Hyperlipidemia|Coronary artery disease|Heart failure|Asthma|Diabetes|Malignancy|Transplantion|Chronic kidney disease NaN NaN NaN Structured
https://doi.org/10.1016/j.ejim.2020.05.011 NaN NaN Italy ITA Interventional 51 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs|Imaging NaN Age greater than 18 years|Respiratory rate greater than equal to 30 per minutes|SpO2 less than 93% while breathing room air|PaO2/FiO2 less than 250 mmHg|Interleukin-6 plasma level greater than 40pg/mL Age|Sex Temperature|Charlson Comorbidity index White blood cell count|Lymphocyte count|Neutrophil count|Lactate dehydrogenase|Aspartate aminotransferase|Alanine aminotransferase|C-Reactive protein|D-Dimer|Interleukin-6 Cardiovascular disease|Hypertension|Diabetes|Chronic Lung disease|Cancer|Rheumatalogic disease|HIV|Chronic heapatitis C|Previous tuberculosis Hydroxychloroquine|Lopinavir/Ritonavir|Remdesivir|Antibiotics|Tocilizumab CT scan Hospitalization|Death Structured
https://doi.org/10.1016/j.ejim.2020.05.021 NaN NCT04318366 Italy ITA Interventional 65 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs|Imaging NaN Diagnosis of COVID-19 confirmed upon reverse-transcriptase Polymerase Chain Reaction (RT-PCR) positivity for SARS-CoV-2 on nasopharyngeal swab|Hyper-inflammation defined as elevation in either C-Reactive protein (CRP, greater than equal to 100 mg/L, normal values less than 6 mg/L) or ferritin (greater than equal to 900 ng/mL, normal value less than 400 ng/mL), in the presence of increased lactate de-hydrogenase (LDH, greater than 220 U/L)|Severe respiratory involvement defined by typical radiological findings at chest X-ray and/or computed tomography (CT) scan, in the presence of an oxygen saturation (SaO2) less than equal to 92% while breathing ambient air or a ratio of the partial pressure of oxygen (PaO2) to the fraction of inspired oxygen (FiO2) (PaO2:FiO2) less than equal to 300 mmHg Age|Sex Temperature PaO2/FiO2|C-Reactive protein|Lactate dehydrogenase|Non invasive ventilation (NIV) Arterial hypertension|Chronic obstructive pulmonary disease|Cancer|Coronary artery disease|Type-2 diabetes|Chronic kidney disease Tocilizumab CT scan Hospitilization|Death|Discharge Structured
https://doi.org/10.1101/2020.08.23.20179838 NaN NaN USA USA|JPN Observational 354 NaN Demographic|Laboratory|Comorbidities NaN NaN Age|Sex|BMI NaN Alanine aminotransferase|Activated partial thromboplastin time|Aspartate aminotransferase|Absolute lymphocyte count|Absolute neutrophil count|Absolute reticulocyte count|Albumin|Blood urea nitrogen|Total bilirubin|C-Reactive protein|Creatinine|D-Dimer|Erythrocyte sedimentation rate|Ferritin|Glucose|Hemoglobin|Interleukin-1 beta|Interleukin-10|Interleukin-6|Lactate dehydrogenase|PT|Platelet count|Procalcitonin|Troponin level|White blood cell count|ANC-ALC-ratio Lymphoma cancer|Lung cancer|Leukemia cancer|Hypertension|Cardiac arrest|Chronic lower respiratory disease NaN NaN NaN NaN
https://doi.org/10.1101/2020.10.15.20209817 NaN ISRCTN83971151 NaN NaN Longitudinal 11266 NaN Laboratory|Clinical NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
https://doi.org/10.1101/2020.10.15.20209817 NaN NCT04315948 France FRA Longitudinal 3100 NaN Laboratory|Clinical NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
https://doi.org/10.1001/jama.2020.4326 NaN NaN USA USA Observational 21 NaN Clinical|Laboratory|Comorbidities|Imaging NaN NaN NaN Temperature White blood cell count|Absolute lymphocyte count|Hemoglobin|Platelet count|Sodium|Creatinine|Total bilirubin|Alkaline phosphatase|Alanine aminotransferase|Aspartate aminotransferase|Creatinine kinase|Venous lactate|Troponin level|Brain-type natriuretic peptide|Procalcitonin Asthma|Chronic obstructive pulmonary disease|Congestive heart failure|Diabetes|Rheumatalogic disease|Obstructive sleep apnea|Chronic kidney disease|End stage renal failure|History of solid organ transplantion|Cirrhosis|Immunosuppression NaN CT scan Death|Remains critically ill and requires mechanicalventilation|Survived to transfer out of ICU|Length of follow-up for those who survived or remaincritically ill NaN
https://doi.org/10.1101/2020.03.09.20032896 NaN NaN USA USA Longitudinal 12 NaN Demographic|Laboratory|Comorbidities|Drugs|Imaging NaN NaN Age|Sex NaN SpO2|Aspartate aminotransferase|Alanine aminotransferase|White blood cell count|Procalcitonin Cardiac arrest|Hypertension|Diabetes|Chronic Lung disease|High cholesterol|Fatty liver disease|Hepatitis B Remdesivir CT scan Critical Care Unstructured
https://doi.org/10.1016/j.tmaid.2020.101663 NaN NaN France FRA Observational 80 NaN Demographic|Clinical|Comorbidities|Drugs|Imaging NaN NaN Age|Sex Temperature NaN Cancer|Diabetes|Coronary artery disease|Hypertension|Chronic respiratory diseases|Obesity|Immunosuppressive treatment Hydroxychloroquine|Azithromycin|Ceftriaxone CT scan Death|Discharged|Hospitalization NaN
https://doi.org/10.1056/NEJMoa2004500 NaN NaN USA USA Observational 24 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs|Imaging NaN NaN Age|Sex|BMI Temperature|Heart Rate|Respiratory rate White blood cell count|Lymphocyte count|Aspartate aminotransferase|Alanine aminotransferase|Lactate|Serum creatinine|Troponin level|Platelet count|Bilirubin|Creatine kinase Asthma|Cancer|Chronic analysis|Chronic kidney disease|Chronic obstructive pulmonary disease|Diabetes|Hemorrhagic or ischemic stroke|Human immunodeficiency virus|Obstructive sleep apnea Hydroxychloroquine|Lopinavir/Ritonavir CT scan Death|Discharged|Hospitalization NaN
https://doi.org/10.1101/2020.04.01.20047381 NaN NaN Germany DEU Observational 40 NaN Demographic|Clinical|Laboratory|Comorbidities NaN NaN Age Respiratory rate|Pulse Lymphoctye count|C-Reactive protein|Bilirubin|White blood cell count|Lactate dehydrogenase|Procalcitonin|Interleukin-6|Thrombocyte count|Troponin level|Creatinine|D-Dimer|Ferritin Hypertension|Diabetes|Coronary artery disease|Chronic obstructive Lung disease NaN NaN Critical Care NaN
https://doi.org/10.1016/j.medmal.2020.03.006 NaN NaN France FRA Observational 11 NaN Clincal|Comorbidities|Drugs|Viral load NaN NaN Age NaN NaN Obesity|Solid cancer|Hematalogical cancer|HIV Hydroxychloroquine|Azithromycin NaN Death|Critical Care NaN
https://doi.org/10.1056/NEJMoa2001191 NaN NaN USA USA Observational 1 NaN Demographic|Clinical|Laboratory|Drugs|Imaging|Epidemiological NaN NaN Age|Sex Temperature|Blood Pressure|Pulse|Oxygen Saturation White blood cell count|Red blood cell count|Absolute neutrophil count|Absolute lymphocyte count|Platelet count|Hemoglobin|Hematocrit|Sodium|Potassium|Chloride|Calcium|Carbon dioxide|Anion gap|Glucose|Blood urea nitrogen|Creatinine|Total protein|Albumin|Total bilirubin|Procalcitonin|Alanine aminotransferase|Aspartate aminotransferase|Alkaline phosphatase|Fibrinogen|Lactate dehydrogenase|Prothrombin time||Creatine kinase|Venous lactate NaN Remdesivir|Vancomycin|Cefepime CT scan NaN Unstructured
https://doi.org/10.1542/peds.2020-0702 NaN NaN China CHN Observational 2143 NaN Demographic|Laboratory|Comorbidities|Imaging|Epidemiological|Severity of illness NaN NaN Age|Gender NaN White blood cell count|Lymphocyte count|C-Reactive protein Fever|Respiratory symptoms|Digestive symptoms (e.g., vomiting, nausea and diarrhea)|Fatigue NaN X ray NaN NaN
https://doi.org/10.1101/2020.04.26.20073411 NaN NaN USA USA Observational 3055 Non-Hispanic|Latino|Hispanic|Latino|Unknown Demographic|Clinical|Laboratory NaN NaN Age|Sex NaN NaN Hypertension|Atrial fibrillation|Coronary artery disease|Heart failure|Stroke|Chronic kidney disease|Diabetes|Asthma|Chronic obstructive pulmonary disease|Cancer NaN NaN Mortality Unstructured
https://doi.org/10.1001/jama.2020.17022 NaN NCT02735707 Australia|Canada|France|Ireland|the Netherlands|New Zealand|the United Kingdom|and the United States. GBR,USA Longitudinal 614 White|Asian|Black|Mixed|Other Demographic|Clinical NaN NaN Age|Sex|BMI NaN NaN NaN NaN NaN NaN Unstructured
https://doi.org/10.1101/2020.06.17.20133579 NaN EudraCT number: 2020-001934-37 Spain ESP Longitudinal 85 NaN Demographic|Laboratory|Comorbidities|Drugs NaN Symptom duration of atleast 7 days|Radiological evidence of Lung disease in chest X-ray or CT scan|ModeRate to severe disease with abnormal gas exchange: PaFi ( PaO2/FiO2) less than 300 or SAFI (SAO2/FiO2) less than 400 or atleast 2 criteria of the RESCIA-COVID Respiratory Severity Scale (BCRSS)|Laboratory parameters suggesting a hyper-inflammatory state: serum C-Reactive Protein (CRP) greater than 15 mg/dl, D-Dimer greater than 800 mg/dl, ferritin greater than 1000 mg/dl or Interleukin-6 levels greater than 20 pg/ml. Age|Sex NaN SAFI(SaO2/FiO2)|Creatinine|Lymphocyte count|Platelet count|C-Reactive protein|D-Dimer|Ferritin Hypertension|Cardiac arrest|Respiratory disease|Diabetes Azithromycin|Hydroxychloroquine|Lopinavir/Ritonavir|Methylprednisolone| NaN ICU admission|Non invasive ventilation|Mortality NaN
https://doi.org/10.1016/j.jsbmb.2020.105751 NaN NCT04366908 Spain ESP Longitudinal 76 NaN Demographic|Laboratory|Comorbidities|Drugs NaN NaN Age|Sex NaN PaO2/FiO2|C-Reactive protein|Lactate dehydrogenase|D-Dimer|Lymphocyte count|Ferritin|Interleukin-6 Lung disease|Chronic kidney disease|Diabetes|High blood pressure|Cardiovascular disease|Immunosuppressed & Transplantioned Calcifediol|Hydroxychloroquine|Azithromycin NaN ICU|Death|Discharged Unstructured
https://doi.org/10.1101/2020.07.01.20139857 NaN NCT04342182 Netherlands NLD Longitudinal 86 NaN Demographic|Laboratory|Comorbidities|Drugs|Disease severity NaN COVID-19 related symptoms for 10 days and had been admitted to the hospital for 2 days|Tested positive for anti-SARS-CoV-2 antibodies|Ig ratio was greater than 10 Age|Sex NaN C-Reactive protein|Ferritin|Lactate dehydrogenase|Lymphocyte count|Bilirubin|WHO COVID-19 disease severity score|PRNT50 titer|Wantai ELISA positive Diabetes|Hypertension|Cardiac arrest|Pulmonary disease|Cancer|Immunodeficiency|Chronic kidney disease|Liver cirrhosis Chloroquine|Azithromycin|Lopinavir/Ritonavir|Tocilizumab|Anakinra NaN Death|Hospitalizaiton NaN
https://doi.org/10.1001/jama.2020.10044 NaN ChiCTR2000029757 China CHN Longitudinal 103 NaN Demographic|Clinical|Laboratory|Viral load|Comorbidities NaN Signed informed consent|Aged at least 18 years|COVID-19 diagnosisbased on polymerase chain reaction (PCR) testing|Posi-tive PCR result within 72 hours prior to randomization|Pneumonia confirmed by chest imaging|Clinical symp-toms meeting the definitions of severe or life-threatening COVID-19|Acceptance of random group assignment|Hospital admission|Willingness to participate in allnecessary research studies and be able to complete the study follow-up|No participation in other clinical trials,such as antiviral trials, during the study period Age|Sex Temperature|Respiratory rate|Heart Rate|Systolic blood pressure White blood cell count|Neutrophil count|Platelet count|C-Reactive protein|Interleukin-6|Prothrombin time|Activated partial thromboplastin time|Thrombin time|Fibrinogen|D-Dimer|Alanine aminotransferase|Aspartate aminotransferase|Urea nitrogen|Serum creatinine Hypertension|Cardiovascular disease|Cerebrovascular disease|Diabetes|Liver disease|Cancer|Kidney disease NaN NaN Mortality Structured
https://doi.org/10.1101/2020.04.03.20052001 NaN NCT04426344 USA USA Longitudinal 20 NaN Demographic|Clinical|Laboratory NaN Patients above the age of 18 years old|Patients with a diagnosis of COVID-19 on mechanical ventilation|Patient maximum baseline temperature (within previous 12 hours) less than 38.3°C|Patients must have a surrogate or legally authorized representative able to understand and critically review the informed consent form Age|Sex|Height|Weight Temperature|Blood Pressure|Heart Rate|Respiration Rate Complete blood count (CBC)|Chemistry profiles|Liver function tests|C-Reactive protein|Ferritin|D-Dimer|Arterial blood gas for determination of PaO2 NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.04.07.20056762 www.unmc.edu/publichealth/departments/biostatistics/jianghu-dong.html NaN China CHN Observational 167 NaN Demographic|Clinical|Laboratory|Comorbidities|Imaging NaN NaN Age|Sex Temperature|Pulse|Respiratory rate|Blood Pressure C-Reactive protein|White blood cell count|Red blood cell count|Lymphocyte count|Hemoglobin|Plasma Prothrombin time determination|Thrombin time|Activated partial thromboplastin time|D-Dimer|Alanine aminotransferase|Urea nitrogen|Fibrinogen|Eosinophil count|Hematocrit High blood pressure|Diabetes|Cardiogenic diseases|Lung disease|Anaemia|Stroke|Kidney disease|Surgery|Liver disease NaN CT scan NaN NaN
https://doi.org/10.1128/AAC.01897-20 https://rctportal.niph.go.jp/en/detail?trial_id=jRCTs041190120 JPRN-jRCTs041190120 Japan JPN Interventional 86 NaN Proportion of subjects with clearance of SARS-CoV2 in nasopharyngeal swab by Day 6 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04423991 NCT04423991 USA USA Interventional 290 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
NaN https://clinicaltrials.gov/show/NCT04358510 NCT04358510 USA USA|JPN Observational 114 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
https://doi.org/10.1002/joa3.12405 https://clinicaltrials.gov/show/NCT04395664 NCT04395664 Denmark DNK Observational 1000 NaN In-hospital mortality during hospitalization and a confirmed COVID-19 diagnosis|Incident intensive care unit admission during hospitalization and a confirmed COVID-19 diagnosis|Incident pulmonary embolism during hospitalization and a confirmed COVID-19 diagnosis|Incident cardiac arrest during hospitalization and a confirmed COVID-19 diagnosis|Incident hypoxic respiratory failure during hospitalization and a confirmed COVID-19 diagnosis NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
NaN http://www.drks.de/DRKS00021424 DRKS00021424 Germany DEU Observational 360 NaN Omics (oropharyngeal mikrobiota) NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.mayocpiqo.2020.07.003 http://www.drks.de/DRKS00021658 DRKS00021658 Germany DEU Observational 100 White|African American|Hispanic|Other Demographic|Clinical|Laboratory|Comorbidities NaN NaN Age|Sex|BMI NaN NaN Hypertension|Diabetes|Hyperlipidemia|Cardiac arrest|Chronic kidney disease|Chronic obstructive pulmonary disease|Stroke or dementia|Smoking|Malignancy|Obesity NaN NaN NaN NaN
NaN http://isrctn.com/ISRCTN13311119 ISRCTN13311119 India IND Interventional 116 NaN Laboratory|Viral load NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://isrctn.com/ISRCTN87832712 ISRCTN87832712 Italy ITA Observational > 20 NaN Oral microbiome|Cytokine|Viral load NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://isrctn.com/ISRCTN10980107 ISRCTN10980107 UK GBR Observational 10000 NaN Laboratory|Clinical|Questionnaires|Viral load|Biosampling for omics NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://isrctn.com/ISRCTN14990068 ISRCTN14990068 Switzerland CHE Observational 3200 NaN Viral load|Hospital stay|Questionnaries NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://www.isrctn.com/ISRCTN44324934 ISRCTN44324934 UK GBR Longitudinal 135 NaN Viral load|Serum antibody level NaN Any patient-facing clinical staff member working regularly in the Children’s Emergency Department (CED) of Bristol Royal Hospital for Children, including doctors, nurses and healthcare assistants Age|Sex NaN NaN NaN NaN NaN NaN NaN
NaN http://www.isrctn.com/ISRCTN64783542 ISRCTN64783542 UK GBR Longitudinal 1000 NaN Demographic|Coagulation parameters|Blood clotting capability|Clinical|Laboratory NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://www.isrctn.com/ISRCTN45562523 ISRCTN45562523 UK GBR Observational 5782649 NaN Viral load|Hospital stay|ICD10 codes for hospital discharge diagnoses|CCU NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.ijid.2020.11.149 https://www.isrctn.com/ISRCTN74727214 ISRCTN74727214 Oman OMN Retrospective 75 NaN Inflammatory biomarker|IMV NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://www.isrctn.com/ISRCTN13035264 ISRCTN13035264 UK GBR Interventional 1063 Hispanic or Latino|Not Hispanic or Latino|Unknown or Not Reported Demographic|Laboratory|Drugs|Comorbidities|Serious adverse events (SAEs)|Clinical Alanine transaminase (ALT) or Aspartate transaminase (AST) greater than 5 times the upper limit of normal|Estimated glomerular filtration rate (eGFR) less than 30 ml/min (including patients receiving hemodialysis or hemofiltration)|Pregnancy or breast feeding|Anticipated discharge from the hospital or transfer to another hospital which is not a study site within 72 hours|Allergy to any study medication NaN Age|Sex NaN Alanine transaminase|Aspartate transaminase|Creatinine|Glucose|Hemoglobin|Platelet count|Prothrombin time|Total bilirubin|White blood cell count|Neutrophil count|Lymphocyte count|Monocyte count|Basophil count|Eosinophil count Coagulopathy|Febrile neutropenia|Anaemia|Cardiac arrest|Atrial fibrillation|Cardio-respiratory arrest|Myocardial infarction|Supraventricular tachycardia|Ventricular tachycardia|Acute myocardial infarction|Cardiac failure|Cardiogenic shock|Acute coronary syndrome|Arrhythmia|Palpitations|Pulseless electrical activity|Ventricular fibrillation|Cardiac tamponade Remdesivir NaN Death|Hospitalizaiton NaN
NaN https://www.isrctn.com/ISRCTN40302986 ISRCTN40302986 Nigeria NGA Double-blind clinical trial 45 NaN Viral load|Clinical NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
NaN http://www.anzctr.org.au/TrialSearch.aspx ACTRN12620000554965 Australia AUS Longitudinal 300 NaN Immunology|Lung and gut microbiome NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://www.anzctr.org.au/TrialSearch.aspx ACTRN12620000421932 Australia AUS Longitudinal 10000 NaN Clinical|ICU NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04327804 NCT04327804 USA USA Longitudinal 120 NaN Viral load NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04330599 NCT04330599 UK GBR Longitudinal 12000 NaN Diverse clinical and social end points NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1007/s10554-020-02010-4 https://clinicaltrials.gov/show/NCT04358952 NCT04358952 France FRA Longitudinal 50 NaN Demographic|Clinical|Laboratory|Comorbidities|Viral load|Electrocardiogram|Inflammatory parameter NaN NaN Age|Sex|BMI Systolic Arterial pressure|Diastolic Arterial pressure|Heart Rate High-sensitivity Troponin|NT-proBNP|Creatinine|Leukocyte count|Lymphocyte count|Platelet count|Hemoglobin|C-Reactive protein|Alanine aminotransferase|Aspartate aminotransferase|Estimated glomerular filtration rate Hypertension|Diabetes|Hypercholesterolemia|Obesity|Cerebrovascular disease|Chronic renal failure|Chronic obstructive pulmonary disease|Sleep disordered breathing NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04368143 NCT04368143 Belgium BEL Longitudinal 100 NaN B and T cell repertoires NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04378777 NCT04378777 USA USA Longitudinal 2000 NaN Clinical|ICU|Biosampling NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04385108 NCT04385108 France FRA Longitudinal 170 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04393155 NCT04393155 USA USA Longitudinal 225 NaN Immunology|FVC|FEV1 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1007/s00125-020-05180-x https://clinicaltrials.gov/show/NCT04324736 NCT04324736 France FRA Observational 1317 Europid|Middle East North Africa|African or Caribbean|Asian Demographic|Laboratory|Comorbidities NaN Hospitalisation in a dedicated COVID-19 unit with COVID-19 diagnosis confirmed biologically (by SARS-CoV-2 PCR test) and/or clinical-ly/radiologically (i.e. as ground-glass opacity and/orcrazy paving on chest computed tomography [CT]scan)|Personal history of diabetes or newly diag-nosed diabetes on admission Age|Sex|BMI NaN Positive SARS-CoV-2 PCR|Admission plasma glucose|Plasma creatinine|Estimated glomerular filtration rate|Alanine aminotransferase|Aspartate aminotransferase|Glutamyl transferase|Hemoglobin|White blood cell count|Lymphocyte count|Platelet count|D-Dimer|C-Reactive protein|Lactate dehydrogenase|Fibrinogen|Creatinine phosphokinase Heart failure|Liver cirrhosis|Cancer|Chronic obstructive pulmonary disease|Obstructive sleep apnea|Organ failure|End stage renal failure NaN CT scan Death|Discharged NaN
NaN http://www.drks.de/DRKS00023418 DRKS00023418 Germany DEU Longitudinal 3000 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN http://isrctn.com/ISRCTN15634328 ISRCTN15634328 UK GBR Longitudinal 2000 NaN Antibody titer NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.jphys.2020.03.011 http://www.ensaiosclinicos.gov.br/rg/RBR-2f9k8p/ RBR-2f9k8p Brazil BRA Longitudinal 2000 NaN Clinical NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ensaiosclinicos.gov.br/rg/RBR-7nky44/ RBR-7nky44 Brazil BRA Observational 703 NaN Clinical NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04337762 NCT04337762 USA USA Observational 100000 NaN Clinical NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1038/s41598-021-84356-w https://clinicaltrials.gov/show/NCT04411576 NCT04411576 Sweden SWE Observational 40000 NaN Demographic|Sick leave records|Clinical|Sequencing NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1172/JCI141772 https://clinicaltrials.gov/show/NCT04355611 NCT04438629 Italy ITA Observational 80 NaN Immunology|Pao2/FiO2 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.msard.2020.102482 https://clinicaltrials.gov/show/NCT04355611 NCT04355611 France FRA Observational 2000 NaN 7-point severity scale at Nadir NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04347694 NCT04347694 Austria AUT Observational 400 NaN Demographic|Laboratory|Comorbidities|COVID-19 diagnostic NaN NaN Age|Sex|BMI NaN IgG|IgA|IgM Hypertension|Diabetes|Cornoary artery disease|Chronic kidney disease|Lung disease|Autoimmune disease|Cancer NaN NaN NaN NaN
https://doi.org/10.1186/s13054-020-03123-x NaN ChiCTR2000029770 China CHN Observational 828 NaN Demographic|Clinical|Imaging|Laboratory|Medical records NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
https://doi.org/10.1101/2020.07.17.20155937 NaN NaN Sweden SWE Observational 105 NaN Demographic|Laboratory|COVID-19 diagnostic NaN NaN Age|Sex NaN Interleukin-6|PSV ID50|IgG (Spike)|IgG (Receptor binding domain)|IgM (Spike)|IgM (Receptor binding domain)|IgA (Spike)|IgA (Receptor binding domain) NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.06.08.20125245 NaN NaN Spain ESP Observational 1229 NaN Demographic|Clinical|Laboratory|Comorbidities|Drugs NaN Heightened high CRP levels Age|Sex Heart Rate|Systolic blood pressure|Temperature|Oxygen Saturation Absolute lymphocyte count|Absolute neutrophil count|Lactate dehydrogenase|Alanine aminotransferase|Urea|C-Reactive protein|D-Dimer|Interleukin-6 Hypertension|Diabetes|Congestive heart failure|Coronary artery disease|Chronic kidney disease|Lung disease Tocilizumab NaN ICU|Mortality NaN
https://doi.org/10.1056/NEJMoa2028836 https://clinicaltrials.gov/show/NCT04356937 NCT04356937 USA USA Interventional 243 NaN Clinical|ICU|Ordinal scale scores NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.07.02.20145565 NaN NaN USA USA Observational 205 Hispanic|Non-Hispanic African American|Non-Hispanic White|Others Demographic|Laboratory|Comorbidities|Drugs|ICU transfer|Intubation|In-hospital mortality NaN Age greater than 18years old|Confirmed cases of SARS-CoV-2 by PCR method|Admitted in general wards|PaO2/FiO2 less than 300 if Arterial blood gas was available or SpO2/Fio2(SF)ratio kess than 440|Bilateral infiltRate on chest imaging validated by radiology staff Age|Sex|BMI NaN PaO2/FiO2|SpO2/FiO2|Sequential Organ Failure Assessment|Hemoglobin|White blood cell count|Absolute lymphocyte count|Platelet count|Globular filtration rate|Aspartate aminotransferase|Alanine aminotransferase|Procalcitonin|Ferritin|Lactate dehydrogenase|D-Dimer|C-Reactive protein|Interleukin-6 Obesity|Hypertension|Diabetes|Chronic Lung disease|Cancer|Coronary artery disease|Heart failure Corticosteriod|Hydroxychloroquine|Tocilizumab|Enoxaparin therapeutic dose NaN NaN NaN
NaN NaN NCT04370262 USA USA Interventional 942 NaN Clinical|7-point ordinal scale NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/S2213-2600(20)30268-X https://clinicaltrials.gov/show/NCT04365959 NCT04365959 Italy ITA Observational 56 NaN Demographic|Laboratory|Comorbidities|Anthropometrics|Arterial blood gas|Ventilation parameters|Oxygenation NaN NaN Age|Sex|BMI NaN Sodium|Potassium|Chlorine|Creatinine|Urea|White blood cell count|Platelet count|Hemoglobin|Hematocrit|Bilirubin|C-Reactive protein|Procalcitonin|Lactate dehydrogenase|Aspartate aminotransferase|Alanine aminotransferase|Activated partial thromboplastin time|D-Dimer|pH|PaO2|PaCO2|SaO2 Previous myocardial infarction|Congestive heart failure|Hypertension|Vascular disease|Chronic bronchopulmonary disease|Gastric or liver disease|Diabetes|Chronic kidney disease|Solid malignancy NaN NaN Death|Hospitalizaiton NaN
https://doi.org/10.1007/s10875-020-00839-x https://clinicaltrials.gov/show/NCT04365959 NCT04262921 France FRA Observational 5000 NaN Clinical|Biological|Radiological and virological assessments|Immunology NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1038/s41467-020-17240-2 NaN NaN China CHN Observational 41 NaN Demographic|Clinical|Laboratory|Comorbidities NaN NaN Age|Sex Temperature Leukocyte count|Neutrophil count|Lymphocyte count|Platelet count|Hemoglobin|Activated partial thromboplastin time|Prothrombin time|Prothrombin time|D-Dimer|Albumin|Alanine aminotransferase|Aspartate aminotransferase|Total bilirubin|Serum creatinine|Lactate dehydrogenase|Interleukin-6|C-Reactive protein|Procalcitonin|Erythrocyte sedimentation rate|Serum ferritin Hypertension|Diabetes|Malignancy|Chronic liver disease NaN NaN NaN NaN
https://doi.org/10.1016/j.cmet.2020.06.015 https://clinicaltrials.gov/show/NCT04330586 NCT04330586 Korea KOR Interventional 94 NaN Clinical|Viral load|ICU NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.cmet.2020.06.015 NaN NaN China CHN Observational 13981 NaN Demographics|Clinical|ICU NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04407273 NCT04407273 Spain ESP Observational 1200 NaN WHO SARS-CoV-2 scale of severity (9 steps) NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.cels.2020.10.003 https://covid-omics.app NaN USA USA Observational 128 White|Black|Asian|Hispanic|Other Demographic|Clinical|Laboratory|RNA-seq|Drugs|High-resolution mass spectrometry|WHO ordinal score at 28 days|HFD-45 NaN NaN Age|Sex|BMI NaN Ferritin|C-Reactive protein|D-Dimer|Procalcitonin|Lactate|Fibrinogen|Albumin|White blood cell count|Hemoglobin|Corpuscular volume|Platelet count|Neutrophil count|Lymphocyte count|Monocyte count|Eosinophil count|PaO2/FiO2|Positive-end expiratory pressure|Inspiratory plateau NaN Hydroxychloroquine|Replacement therapy (pre-enrollment)|Antibiotics|Antiviral|IL6 - antagoinist|Convalescent plasma|Steroids|Therapeutic anticoagulation NaN NaN NaN
https://doi.org/10.1016/j.eclinm.2020.100449 https://www.risc-19-icu.net NCT04357275 Switzerland CHE Observational 10000 NaN ICU NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1148/radiol.2020202422 https://clinicaltrials.gov/show/NCT04362930 NCT04362930 France FRA Observational 2000 NaN Demographic|ICU|Brain MRI| NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.06.11.20128041 https://www.risc-19-icu.net NCT04357275 (partly) Switzerland CHE Observational 28 NaN Demographic|Comorbidities|ICU|Laboratory NaN NaN Age|Sex|BMI NaN NaN Coronary artery disease|Chronic Heart failure|Peripheral artery disease|Arterial hypertension|Diabetes NaN NaN NaN NaN
https://doi.org/10.1186/s13054-020-03286-7 https://clinicaltrials.gov/show/NCT04350073 NCT04350073 USA USA Observational 120 NaN ICU|Laboratory|Metabolic parameter (e.g.|pREE) NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04401033 NCT04401033 Spain ESP Observational 450 NaN Clinical|Laboratory NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1001/jamaoto.2020.5074 https://clinicaltrials.gov/show/NCT04407494 NCT04407494 France FRA Observational 809 NaN Diagnostic values of anosmia and ageusia for COVID-19|Diagnostic values of CODA (Clinical Olfactory dysfunction Assessment) NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04358536 NCT04358536 USA USA Observational 230 NaN Clinical NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.rmed.2021.106312 https://clinicaltrials.gov/show/NCT04407260 NCT04407260 USA USA Observational 136 NaN Oxygen Saturation||Intubation/mechanical Ventilation NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04480060 NCT04480060 Turkey TUR Observational 100000 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
https://doi.org/10.1007/s11239-020-02235-z https://clinicaltrials.gov/show/NCT04374617 NCT04374617 Spain ESP Observational 230 NaN NA NaN NaN NaN NaN NaN NaN NaN NaN Venous thromboembolisms|Mortality NaN
NaN https://clinicaltrials.gov/show/NCT04466644 NCT04466644 USA USA Observational 340 NaN Prevalence of contagiousness in asymptomatic individuals by PCR with nasopharyngeal swabs|Ratio of asymptomatic immunized (IgG) population NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/show/NCT04409249 NCT04409249 Turkey TUR Observational 155 NaN Factors affecting prognosis NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1111/aas.13694 https://clinicaltrials.gov/show/NCT04337502 NCT04337502 Netherlands NLD Observational 300 NaN Predictive performance NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04479137 NCT04479137 Turkey TUR Observational 5000 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04445961 NCT04445961 Russia RUS Observational 117 Optimum positive end-expiratory pressure NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.amsu.2020.11.006 https://clinicaltrials.gov/ct2/show/NCT04480580 NCT04480580 Italy ITA Observational 100 NaN Demographic|Imaging|Seroprevalence of SARS-CoV-2 NaN NaN Age|Sex NaN NaN NaN NaN CT scan NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04374123 NCT04374123 Ecuador ECU Observational 111 NaN COVID-19 infection in the staff documented via PCR|serum levels of IgG and IgM against COVID-19|Endoscopic records of patients treated during the COVID-19 protocol NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04387799 NCT04387799 Italy ITA Observational 520 NaN Serology|Efficacy of CT scan and Serology|Efficacy of different pharmaceutical treatments against Covid-19 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04577105 NCT04577105 Mexico MEX Observational 233 NaN Level of suspicion of SARS-CoV2 infection NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://clinicaltrials.gov/ct2/show/NCT04357535 NCT04357535 Saudi arabia SAU Observational 314 NaN Severity of COVID-19 Infection|PaO2/FiO2 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04412304 NCT04412304 Sweden SWE Observational 166 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Hyponatremia|Mortality|Hyponatremia|ICU NaN
NaN https://ClinicalTrials.gov/show/NCT04453501 NCT04453501 France FRA Observational 132 NaN Risk factor measurements NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04554979 NCT04554979 Egypt EGY Observational 199 NaN GIT manifestations|Disease spectrum and duration NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1093/cid/ciaa601 https://ClinicalTrials.gov/show/NCT04374071 NCT04374071 USA USA Observational 250 NaN Transfer to Intensive care unit (ICU)|Need for Mechanical Ventilation||Development and Severity of ARDS|Length of hospital stay (LOS) NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04393428 NCT04393428 France FRA Observational 100 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.08.06.20169599 https://ClinicalTrials.gov/show/NCT04462393 NCT04462393 Sweden SWE Observational 1563 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality|ICU NaN
NaN https://ClinicalTrials.gov/show/NCT04518735 NCT04518735 Spain ESP Observational 1707 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality|Transfer to the Intensive Care Unit (ICU)|Thromboembolic complications|Major bleeding complications NaN
NaN https://ClinicalTrials.gov/show/NCT04433754 NCT04433754 Turkey TUR Observational 500 NaN NaN NaN NaN NaN NaN C-Reactive protein|D-Dimer Fever|Dyspnea NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04452682 NCT04452682 Egypt EGY Observational 998 NaN ICU NaN NaN NaN NaN NaN NaN NaN NaN Mortality NaN
NaN https://ClinicalTrials.gov/show/NCT04390074 NCT04390074 Sweden SWE Observational 9905 NaN Chronic medications as risk factor of intensive care for COVID-19|Comorbidities as risk factor of intensive care for COVID-19|Chronic medications as risk factor of death during intensive care for COVID-19|Comorbidities as risk factor of death during intensive care for COVID-19 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1101/2020.08.26.20180992 https://ClinicalTrials.gov/show/NCT04488588 NCT04488588 Egypt EGY Observational 1964 NaN Number of co-morbidities in hospitalized patients with COVID-19|Causes of ICU admission NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04341766 NCT04341766 France FRA Observational 106 NaN Characteristics of pulmonary ultrasound for Covid-19 patients|ChaRateristics of pulmonary CT-scan for Covid-19 patients NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04527458 NCT04527458 UK GBR Observational 70000 NaN Case fatality NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1111/aas.13694 https://ClinicalTrials.gov/show/NCT04378582 NCT04378582 Brazil BRA Observational 1589 NaN ICU survival at 28 days|Hospital survival at 60 days|Duration of mechanical ventilation|Need for renal replacement therapy|Complications during the ICU stay NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1371/journal.pone.0244853 https://ClinicalTrials.gov/show/NCT04485169 NCT04485169 Pakistan PAK Interventional 280 NaN Survival|Duration of hospitalization|Timing of PCR negativity|Time to CRS resolution|Complications NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1714/3343.33127 https://ClinicalTrials.gov/show/NCT04318418 NCT04318418 Italy ITA Observational 3400 NaN Severe COVID-19|Death NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04365634 NCT04365634 China CHN Observational 306 NaN Demographic|Clinical|Laboratory|Imaging|Drugs|Comorbidities NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1536/ihj.20-323 https://ClinicalTrials.gov/show/NCT04318301 NCT04318301 China CHN Observational 275 NaN Rate of Death|Severity of pneumonia NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04355871 NCT04355871 Spain ESP Observational 4035 NaN Mechanical ventilation NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
https://doi.org/10.1016/j.thromres.2020.11.001 https://ClinicalTrials.gov/show/NCT04420312 NCT04420312 France FRA Observational 1024 NaN Clinical|Imaging NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04493268 NCT04493268 Argentina ARG Observational 250 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality|ICU NaN
NaN https://ClinicalTrials.gov/show/NCT04292964 NCT04292964 China CHN Observational 201 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN Mortality|Severe state NaN
https://doi.org/10.1093/cid/ciaa601 https://ClinicalTrials.gov/show/NCT04344327 NCT04344327 France FRA Observational 2878 NaN Death Rate|ICU|Ventilation analysis NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN
NaN https://ClinicalTrials.gov/show/NCT04425213 NCT04425213 France FRA Observational 250 NaN NaN NaN NaN NaN NaN NaN NaN NaN NaN ICU|Mortality|Invasive mechanical ventilation NaN

Geographic location of the studies


Serology Studies

Metadata of the studies included in the viewer.

Publication reference URL of Dataset Clinical Trial ID Country Country code Study design Total number of subjects Ethnicity Existent variables Exclusion criteria Inclusion criteria Demographic Clinical variables Laboratory variables Comorbidities Drugs Imaging Endpoint Type of data
PMID:33173900 https://www.medrxiv.org/content/10.1101/2020.11.05.20226654v1.supplementary-material NaN USA USA Longitudinal 29.0 Black|Latino|White|Other Clinical|Demographic|Laboratory NaN NaN Age|Sex|Ethnicity Serum samples IgA|IgG|IgM Diabetes|Obesity|Hypertension|Cardiovascular disease|Renal Disease|Chronic Lung Disease|Stroke NaN Fluorescent detector—the D4Scope log(D4 intensity a.u.) NaN
PMID:33531472 https://github.com/linsemanlab/Grossberg-Koza-et-al-2021 NaN USA USA Longitudinal 107.0 White|Asian|Hispanic|Latino|Spanish Clinical|Demographic|Laboratory NaN NaN Age|Sex|BMI|Ethnicity Questionnaire IgA|IgG|IgM Smoking history|Cardiovascular disease|Diabetes|Autoimmune disease|Tick-Borne illness|Hemochromatosis|Blood related disease NaN Chemuluminescent immunoassay IgA|IgG|and IgM antibody titers Structured
PMID:32994364 https://science.sciencemag.org/content/suppl/2020/09/28/science.abd4250.DC1 NaN USA USA Longitudinal 420.0 Asian|Black|Black_Hispanic|Hispanic|Other|Unknown|White|White_Hispanic Clinical|Demographic|Laboratory NaN NaN Age|Sex|Ethnicity Cohort 1: plasma samples|date of initial symptom onset|symptom type|date of diagnosis|date of symptom cessation|and severity of symptoms/ Cohort 2: Serum samples symptom duration and comorbidities/ Cohort 3: plasma samples|days since symptom onset| results of COVID-19 molecular testing/ Cohort 4: blood sample|demographic|past medical|and clinical data/ Cohort 5 and 6: Remnant serum specimens|onset of symptom/ Cohort 7 and 8: serum samples/ Cohort 9: plasma samples IgG|IgA NaN NaN NaN IgG|IgA antibody titers Structured
PMID:32337590 https://academic.oup.com/cid/article/71/16/2255/5825506#supplementary-data NaN China CHN Longitudinal 41.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex|Epidemiological history Serum samples IgG |IgM|Serological responses to SARS-CoV-2| Detection of nucleocapsid (N) protein and spike (S) glycoprotein NaN NaN Chemuluminescent immunoassay IgG|IgM Structured
PMID:32948854 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498988/, https://data.mendeley.com/datasets/2f73pzdkr4/1 NaN USA USA Longitudinal 445.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples IgA|IgG|IgM Diabetes|Immunosuppression|Lung Disease|Heart Disease NaN Multicolour imaging IgA|IgG|IgM Structured
PMID:32817357 https://stm.sciencemag.org/content/suppl/2020/08/17/scitranslmed.abc3103.DC1 NCT04325646 France FRA Longitudinal 751.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Questionnaire|Sociodemographic information|Underlying medical conditions|History of respiratory symptoms back to 13 January 2020|History of COVID-19 diagnosis before this investigation IgA|IgG|IgM NaN NaN NaN Seroprevalence|optical density|IgG| IgM |IgA reactivity against purified tri-S proteins Structured
PMID:32783920 ttps://doi.org/10.1016/j.immuni.2020.07.020 NaN USA USA Longitudinal 66.0 Asian|Black|White Clinical|Demographic|Laboratory NaN NaN Age|Sex|Ethnicity|Intervention Plasma samples IgA|IgG|IgM NaN Chloroquines|Remdesivir|Tocilizumab|Antibiotics NaN IgA|IgG|IgM Antibody responses Structured
PMID:32897389 https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/clinchem/66/12/10.1093_clinchem_hvaa213/1/hvaa213_supplementary_data.docx?Expires=1621248273&Signature=1f7Y0LlTdMNp-fSuW89LWJYjgx5BD4C4m3k839gAop3uSBnQgks8mXdXUlbZG~S6DDBLpHDhu52qBSfryqSZSkPR4XUPxRc~FM-mlLcRqGQ9ljNwNLFBFwTMJQPIfIaDtzENNP5tJShl~KNx6Amw2eQW4N2VEy~V4dimRThAja1Cmrt0cyMO3tNiqr-1qgFf8oenyeM6BLoVhLOwpn6boi4r0jk9Hze7uyHq~obUiJ0TYjw2ANhcqOkC4OQdw0sW~3rKVf0vaPbjjDZYka3tvuigpMi2a22T-D022iH0-LDVdHWiwow8z8wjSo86aFHXHprijVmmVTgSDYDcGfpwpg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA NaN USA USA Longitudinal 64.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Plasma samples|Patient disposition at time of admission. Was Patient Immunosuppressed?|Fraction of patients admitted to ICU|Fraction of patients intubated| Days between hospitalization and intubation|Length of intubation SARS-CoV-2 S1 and N antigen detection|Serological responses NaN NaN NaN IgG|IgM|and IgA each against S1|Spike|N|and receptor binding domain (RBD) Structured
PMID:33040337 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675426/ NaN China CHN Longitudinal 1056.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Healthy|Asymptomatic|Mild symptoms Serum IgM and IgG antibodies|Serum proteome microarray NaN NaN NaN IgM|IgG responses Structured
PMID:32705575 NaN NaN China CHN Longitudinal 88.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples| Mild/moderate symptoms|Severe(critical symptoms) IgG|IgM|Antibody titer NaN NaN Chemiluminescence immunoassay IgG|IgM Structured
PMID:33397903 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217240/bin/NIHPP2020.04.15.043364-supplement-1.pdf NaN USA|Switzerland USA|CHE Comparative 22.0 NaN Clinical|Laboratory NaN NaN NaN Plasma samples IgG|IgA NaN NaN Human IgG and IgA secondary antibodies conjugated to quantum dot fluorophores Q800 and Q585 IgG|IgA Structured
PMID:32913364 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482996/# NaN China CHN Longitudinal 26.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Throat swab samples|Serum samples|Onset signs and symptoms|Duration of positive viral RNA|ct value of RT-PCR|Lymphocyte|CRP|ESR|IL-6 IgG|IgM Diabetes|Hypertension|Alzheimer's Disease|Cerebral infarction|Liver cyst hormone|interferon atomization|Lopinavir/Ritonavir|Immunoglobulin|Arbidol|Darunavir|Thymosin|Ribavirin NaN IgG|IgM Structured
PMID:32389784 https://www.journalofinfection.com/article/S0163-4453(20)30244-9/fulltext NaN France FRA Longitudinal 22.0 NaN Clinical|Laboratory NaN NaN NaN Serum samples IgM|IgG|Antibody detection NaN NaN NaN IgM|IgG Structured
PMID:33019628 https://www.mdpi.com/2077-0383/9/10/3188/s1 NaN Italy ITA Longitudinal 546.0 NaN Clinical|Demographic|Laboratory Inability to provide informed consent Health care workers (medical doctors, practitioners, post-graduate students, nurses), potentially exposed to SARS-CoV-2 between February and June 2020|Documented SARS-CoV-2 infection by NF swab|Not being hospitalized for COVID-19; For those hospitalized with COVID-19: Documented SARS-CoV-2 infection by NF swab| Being admitted in the ICU between February and June 2020 for COVID-19; For negative controls: sera being collected before 2019 Age|Sex Serum samples|Disease duration|Symptoms IgM|IgG |IgA Obesity|Cardiopulmonary|Diabetes|Renal|Vasculopathy|Multile comorbidities NaN NaN IgM|IgG|IgA|Cytokines|Chemokines Structured
PMID:33177504 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658256/# NaN Australia AUS Longitudinal 5.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serial samples including blood,saliva, NP, swabs, feces and urine|Symptoms recording Anti-S1 salivary IgA|IgG|IgM|Immune profiling NaN NA NaN IgA|IgG|IgM|IL-1α|IL-1β|IL-6|IFNα|TNFα|MIP-1α|MCP-1|IL-8|RANTES|IL-12p70|IL-10|IL-2|IL-5|IL-5|IL-9|IL-13|IFNγ|IL-17A|20,000 randomly selected live single cells per patient per time point Structured
PMID:32511499 https://www.medrxiv.org/content/early/2020/05/14/2020.05.10.20097535.external-links NaN USA USA Cross-sectional 180.0 Asian|Afro American|Non-hispanic Caucasian|Hispanic|Other Clinical|Demographic|Laboratory NaN NaN Age|Sex|Ethnicity Serum samples|Plasma samples|Days since symptom onset|Respiratory failure requiring intubation|Duration of disease|Clinical symptoms IgM|IgG NaN NaN NaN IgG|IgM Structured
PMID:33133098 NaN NaN Italy ITA Longitudinal 2.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Nasopharyngeal swabs|Oxygen saturation on room air|HIGH Resolution CT (HRCT)|Hospitalization weeks|CPAP IgM|IgG|IgA|White cell count|Absolute lymphocyte count|C-reactive protein|Ferritin|Il-6|D-dimer arterial hypertension|trans-catheter ablation of atrial fibrillation|and right hemisphere ischemic stroke. NaN NaN IgM|IgG|IgA Structured
PMID:32711254 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375792/# NaN Singapore SGP Longitudinal 156.0 Chinese|Others Clinical|Demographic|Laboratory NaN NaN Age|Sex|Ethnicity Plasma samples|Temperature |Heart rate| Respiratory rate | Diastolic blood pressure | Systolic blood pressure| Oxygen saturation Haemoglobin|Haematocrit|Platelets|White blood cells|Lymphocytes|Neutrophils|Monocytes|C-reactive protein (CRP)|Creatinine|Lactate dehydrogenase| Alanine aminotransferase (ALT) Diabetes|Hypertension|Others NaN NaN IgG Structured
PMID:32819220 https://doi.org/10.1080/22221751.2020.1813636 NaN Netherlands NLD Longitudinal 330.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Severity of diseases|Recent other influenza-like illness infection IgG|Microarray|Virus neutralization test 50 NaN NaN NaN IgG |Micro-array titres Structured
PMID:33091042 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580996/# NaN Korea KOR Longitudinal 154.0 Korean|Polish Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Symptoms|Symptom onset Time kinetics for IgG and IgM antibodies NaN NaN Cyclic enhanced fluorescence assay IgM|IgG Structured
PMID:33199310 https://bjgpopen.org/content/5/1/bjgpopen20X101137/tab-figures-data CEIID200406001 Chile CHL Longitudinal 522.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Nasopharyngeal swabs IgG|IgM High blood pressure|Diabetes|Asthma or COPD|Cardiovascular disease|Cancer|Smoking| Symptoms ARBs|ACE inhibitors|NSAIDSs|Oral steroids|Inhalator steroids NaN IgG|IgM Structured
PMID:33388574 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836402/#bib0005 NaN Italy ITA Longitudinal 55.0 NaN Clinical|Demographic|Laboratory NaN Only patients with known date of symptoms’ onset were considered. Age|Sex Serum samples|Disease severity|Days from symptom onset|Symptoms| Number of withdrawals per patient IgG NaN NaN Two-step chemiluminescence micropar-ticle immunoassays IgG Structured
PMID:33052354 https://jcm.asm.org/content/59/2/e02489-20/figures-only RSRB STUDY00004836 USA USA Longitudinal 140.0 NaN Clinical|Demographic|Laboratory NaN NaN Age|Sex Serum samples|Estimated date of symptom onset|Days of hospitalization|Intensive care unit [ICU] admission|Death|Symptoms IgG History of smoking|Coronary artery disease|Chronicobstructive pulmonary disease [COPD]|Diabetes NaN Fluorescence IgG Structured
PMID:33322150 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764094/pdf/ijerph-17-09324.pdf NaN Italy ITA Longitudinal 242.0 NaN Clinical|Laboratory NaN Hospital healthcare workers NaN Serum samples IgG|IgM NaN NaN NaN IgG|IgM Structured
PMID:33388575 https://pubmed.ncbi.nlm.nih.gov/33388575/ NaN USA USA Longitudinal 89.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN IgM|IgG|Day of seroconversion caught NaN NaN NaN Survived|Deceased|Immune competent|Immune compromised Structured
PMID:33340166 https://pubmed.ncbi.nlm.nih.gov/33340166/ NaN China CHN Longitudinal 54.0 NaN Laboratory NaN NaN NaN NaN IgM|IgG NaN NaN NaN NaN Structured
PMID:33533813 https://pubmed.ncbi.nlm.nih.gov/33533813/ NaN Brazil BRA Longitudinal 209.0 White|Non white Laboratory|Demographic NaN NaN Age|Sex NaN Katz index|Frail-BR index|Frail-NH index|Complexity of the Long Term Care Facility NaN NaN NaN NaN Structured
PMID:32638712 https://pubmed.ncbi.nlm.nih.gov/32638712/ NaN UK GBR Longitudinal 74.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN IgM|IgA|IgG NaN NaN NaN Death|Discharged Structured
PMID:33139422 https://pubmed.ncbi.nlm.nih.gov/33052354/ NaN USA USA|CHE Longitudinal 140.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN Spike Median fluorescent intensity (MFI)| Receptor Binding Domain (RBD) Median fluorescent intensity (MFI)|Nucleocapsid Median fluorescent intensity (MFI) Asthma|COPD|Diabetes|Hypertension|Obstructive sleep apnea|Coronary artery disease|Cerebrovascular disease|Immunodeficiency / Immunosuppression NaN NaN NaN Structured
PMID:33404891 https://pubmed.ncbi.nlm.nih.gov/33404891/ NaN Estonia EST Longitudinal 100.0 NaN Laboratory|Demographic NaN Availability of leftover sera obtained for routine SARS-CoV-2 serological testing Age|Sex NaN C-Reactive Protein|Ferritin|Dimer-D|Lactose dehydrogenase|Interleukin-6|Total lymphocyte count Arterial Hypertension|Chronic renal disease|Diabetes|Dyslipidemia|Ischemic cardiovascular disease|Myocardial infarction|Pulmonary disease|Tumor NaN NaN NaN Structured
PMID:33555331 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2776019 NaN USA USA Cross-sectional 4675.0 Hispanic|Non Hispanic NaN NaN NaN Age|Sex NaN NaN NaN NaN NaN NaN NaN
PMID:33557402 https://pubmed.ncbi.nlm.nih.gov/33557402/ ISRCTN91064601 Italy ITA Longitudinal 84.0 NaN Laboratory|Demographic NaN Age between 4 and 16 with at least one cohabitant who had been positive for SARS-CoV-2 Age|Sex NaN IgM|IgG NaN NaN NaN NaN Structured
PMID:33608522 https://www.nature.com/articles/s41467-021-21444-5 NaN Australia AUS Longtitudinal 64.0 NaN Laboratory|Demographic NaN NaN NaN NaN IgM|IgG |IgA NaN NaN NaN NaN Structured
PMID:33664294 https://www.nature.com/articles/s41598-021-84387-3 NaN Japan JPN Longitudinal 500.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN N-IgG|S-IgG|N-IgM|S-IgM NaN NaN NaN NaN Structured
PMID:33553482 https://academic.oup.com/ofid/article/8/2/ofaa654/6116757 NaN USA USA|CHE Longitudinal 432.0 Black|White|Hispanic|Other Laboratory NaN NaN NaN NaN Spike IgG|Spike IgM|RBD IgG NaN NaN NaN NaN Structured
PMID:33680466 https://onlinelibrary.wiley.com/doi/full/10.1002/cti2.1258 NaN NaN NaN Longitudinal 15.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN Receptor Binding Domain IgM |Spike IgG|Spike IgA|Nucleocapsid IgG NaN NaN NaN NaN Structured
PMID:33169014 https://www.nature.com/articles/s41590-020-00828-7 NaN USA USA Longitudinal 43.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN IgM|IgA|IgG NaN NaN NaN NaN Structured
PMID:32856707 https://pubmed.ncbi.nlm.nih.gov/32856707/ NaN China CHN Longitudinal 100.0 Chinese Laboratory|Demographic|Clinical NaN Patients confirmed to have COVID-19 by SARS-CoV-2 (RT-PCR) and admitted to any of seven public hospitals in Singapore Age|Sex Temperature|Respiratory rate|Heart rate|Systolic blood pressure|Pulse oximeter oxygen saturation Haemoglobin|Platelet|Lymphocyte|Neutrophil|C-Reactive Protein|Lactate dehydrogenase|Creatinine|Alanine transferase|PCR Ct value at diagnosis Diabetes|Hypertension NaN NaN NaN Structured
PMID:32991844 https://www.sciencedirect.com/science/article/abs/pii/S0092867420312344 NaN Italy|Switzerland|US ITA|CHE|USA Longitudinal 647.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN Serum IgG binding to S|Serum IgG binding to RBD|Serum IgG binding to N NaN NaN NaN NaN Structured
PMID:32727884 https://immunology.sciencemag.org/content/5/49/eabd5709 NaN USA USA Longitudinal 1293.0 Black/Non-Hispanic|White/Non-Hispanic|Hispanic/Latino|Asian|Other/Unknown Laboratory|Demographic NaN NaN Age |Sex NaN IgG|IgM Obesity|Diabetes|Hypertension|Diabetes|Asthma NaN NaN NaN Structured
PMID:32511324 https://www.biorxiv.org/content/10.1101/2020.03.24.006544v1 NaN USA USA Longitudinal NaN NaN Laboratory NaN NaN NaN NaN IgG NaN NaN NaN NaN Structured
PMID:32938700 https://msphere.asm.org/content/5/5/e00802-20 NaN USA USA Longitudinal NaN NaN NaN NaN NaN NaN NaN RBD-biotin|RBD-hFc| RBD-mFc NaN NaN NaN NaN Unstructured
PMID:33227020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682882/ NaN Israel ISR Longitudinal 309.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN IgM|IgG|IgA NaN NaN NaN NaN Structured
PMID:32908997 https://www.medrxiv.org/content/10.1101/2020.09.04.20187088v1 NaN USA USA Longitudinal 159.0 NaN Laboratory NaN Patients without asymptomatic individuals or patients with mild symptoms infected with SARS-CoV-2 Age|Sex NaN NaN NaN NaN NaN Alive|Dead Structured
PMID:33232382 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0242917 NaN Germany DEU Longitudinal 23.0 NaN Laboratory|Demographic NaN Age greater than equal to 18 with a confirmed diagnosis of COVID-19 Age|Sex|BMI NaN PaO2/FiO2|Extracorporeal membrane oxygenation(ECMO) Chronic obstructive pulmonary disease|Arterial hypertension|Coronary artery disease|Diabetes mellitus|Chronic renal insufficiency NaN NaN NaN Structured
PMID:33233405 https://pubmed.ncbi.nlm.nih.gov/33233405/ NaN Belgium BEL Longitudinal 94.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN N-directed IgG|S1-directed IgG|S2-directed IgG|RBD-directed IgG NaN NaN NaN NaN Structured
PMID:33755731 https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiab161/6184123 NaN USA USA|CHE Longitudinal 3418.0 NaN Laboratory NaN NaN Age NaN NaN NaN NaN NaN NaN NaN
PMID:32306864 https://pubmed.ncbi.nlm.nih.gov/32306864/ NaN China CHN Longitudinal 21.0 NaN Laboratory|Demographic NaN NaN Age|Sex NaN Anti SARS-CoV-2 IgG|Anti SARS-CoV-2 IgM NaN NaN NaN NaN Structured
PMID:32476258 https://pubmed.ncbi.nlm.nih.gov/32476258/ NaN USA USA Longitudinal 9.0 Black|Latino|Asian|NH/PI|White Laboratory|Demographic|Clinical NaN NaN Age|Sex|BMI Temperature WBC count|Lymphocyte|Platelets|Creatinine|Aspartate aminotransferase|Alanine aminotransferase|Troponin|C-Reactive Protein|Lactate dehydrogenase|Procalcitonin|D-Dimer Cerebrovascular disease|Continuous renal replacement therapy|Deceased donor renal transplant|Diabetes mellitus|Ground-glass opacities|Hyperlipedimia|Hypertension|Asthma|Dementia|Hypothyroid|Sarcoidosis|Gout|Heart failure with reduced ejection fraction|Upper respiratory symptoms|Rheumatoid arthritis Hydroxychloroquine|Lopinavir/ritonavir| CT scan Discharged ICU|Discharged hospital|Died Structured
PMID:33161369 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590643/ NaN USA USA Longitudinal 427.0 NaN Laboratory|Demographic NaN NaN Age NaN IgM|IgG NaN NaN NaN NaN Structured

Geographic location of the studies